|Blood clot formation in the blood vessel causes obstruction of blood flow in circulatory system is known as thrombosis. If a thrombus is remarkably large sufficient to decrease the blood flow to a tissue,Â hypoxiaÂ can occur and at the same time metabolic products like lactic acidÂ can accumulate. Main cause of Thrombosis is hypercoagulability or injury of endothelial cell etc.The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number ofÂ citationsÂ to recent articles published inÂ science and social science journals in a particular year or period, and is frequently used as aÂ proxyÂ for the relative importance of a journal within its field. It is first devised byÂ Eugene Garfield, the founder of theÂ Institute for Scientific Information.The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.