|It is a type of cardiovascular diseases which affects the blood vessels. It is a clinical condition of large and medium sized arteries which is affected by dysfunction of endothelial cell. Pathogens, cytokines, inflammatory stimuli endothelial cells are factors which causes vascular diseases. Once endothelial cells become activated it release cytokines and chemokines which expresses adhesion molecules on their surface which results in to release of WBC. WBC can infiltrate the blood vessels wall. Stimulation of smooth muscle layer with cytokine further causes thickening of vessel wall and at a final stage it results in to strokes.The top open access journals are peer reviewed scholarly journals of Journal of Vascular Medicine and Surgery. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community.These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI.