Journal of antivirals and antiretroviral is one of the top journals in the current field of virology which publishes novel work in the form of different article types such as research or review articles. This journal acts as a barrier for exchange of scientific knowledge among researchers and scientists.
This mainly involves in the discovery and development of antiretroviral drugs, to prolong life of the humans and discovers compounds, and clinical methods to prevent viral infections. Importantly, it provides the opportunity to study about Virosomes, ant-HIV drugs and HIV antiviral drugs in the field of virology. Antivirals & Virosomes is an internationally recognized journal for scientists involved in basic, applied, and clinical aspects of antiviral and antiretroviral research. It is known that many viruses emerge and re-emerge threatening both animal and human populations.
A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid membrane it may be mono- or bi-layered. Vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells. Virosomes are not able to replicate but are pure fusion-active vesicles.
The development of safe and effective models for the delivery of any prophylactic or therapeutic agent remains an uphill task for pharmaceutical formulation developers. Drug molecules, nucleic acids, carbohydrates, proteins and a variety of other biological and chemical entities are used for attaining pharmacological benefits. However, the major challenge remains in the delivery of these agents to the specific site of action in a time-efficient manner. Among the many drug delivery systems developed, the nano scale technology of virosomes tends to present an established system of delivering the therapeutic agents to the site of pharmacological action. Virosomes are lipid bilayer, unilamellar structures that present viral protein on their surface. They are safe, biocompatible and biodegradable structures that can achieve ideal pharmacological profile once administered into the body. Tissue targeting, immune activation and potentiation are the chief advantages that make them efficient prophylactic and therapeutic agents. The review presents the biopharmaceutical applications of virosomes and the immunological and pharmaceutical considerations that make them efficient agents for targeting spatiotemporal parameters in the body
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Last date updated on October, 2020