Drug metabolism is the study of the movement of the drug. It is also known as xenobiotic metabolism which involves the biochemical change of the drug by an individual or a living organism. In the phase I of the drug metabolism, involves the addition of functional group such as âOH, âCOOH or these functional groups are unmasked if the drug is lipid soluble so that the drug can undergo Phase II reaction. This phase is also called the non-synthetic or non-conjugate reactions. Phase II is also called the synthetic phase, which involves the binding of the drug to endogenous substances which make the drug readily absorbed by kidneys or liver.
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2014