Drug metabolism is the study of the movement of the drug. It is also known as xenobiotic metabolism which involves the biochemical change of the drug by an individual or a living organism. In the phase I of the drug metabolism, involves the addition of functional group such as âOH, âCOOH or these functional groups are unmasked if the drug is lipid soluble so that the drug can undergo Phase II reaction. This phase is also called the non-synthetic or non-conjugate reactions. Phase II is also called the synthetic phase, which involves the binding of the drug to endogenous substances which make the drug readily absorbed by kidneys or liver.
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Last date updated on January, 2021