alexa Xenobiotic Metabolism Review Articles|OMICS International|Journal Of Drug Metabolism And Toxicology

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Xenobiotic Metabolism Review Articles

Drug metabolism is the study of the movement of the drug. It is also known as xenobiotic metabolism which involves the biochemical change of the drug by an individual or a living organism. In the phase I of the drug metabolism, involves the addition of functional group such as –OH, –COOH or these functional groups are unmasked if the drug is lipid soluble so that the drug can undergo Phase II reaction. This phase is also called the non-synthetic or non-conjugate reactions. Phase II is also called the synthetic phase, which involves the binding of the drug to endogenous substances which make the drug readily absorbed by kidneys or liver. Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results. Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications. The concept of "review article" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.
 
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Last date updated on September, 2014