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Aim: To determine the disease burden in terms of clinical profile and management outcome of diabetic foot complication at a tertiary care hospital in a developing country. Material and methods: In this descriptive study, data were collected from the medical record of patients with diabetic foot ulcers (DFU) who were referred to .. Read More
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Background: Diabetic foot ulcers (DFUs) are a common complication of diabetes. Non-healing or chronic DFUs are a growing problem associated with wound-related morbidities and high costs. Previously the treatment of chronic DFUs with a cryopreserved placental membrane (commercially known as Grafix®), in a controlled randomize.. Read More
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Introduction: Randomised controlled trial is a specific type of scientific experiment, and the gold standard for a clinical trial. RCTs are often used to test the efficacy or effectiveness of various types of medical intervention within a patient population. RCTs may also provide an opportunity to gather useful information about.. Read More
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Autoimmunity Markers in Patients with Type 2 Diabetes
Introduction: Diabetes is a growing social and epidemiological problem. Frequent diabetes complications occurrence has an impact on a higher percentage prevalence of the cardiovascular, kidneys, nervous system and vision diseases. Aim: The aim of the study was to evaluate the incidence of immunological markers in patients with t.. Read More
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Contemporary data indicates that the prevalence of diabetes mellitus will increase by year 2030, where up to 50% develop neuropathy, and about a quarter will develop neuropathic pain. The purported immunocompromised diabetic state makes them also susceptible to various infections, for instance, herpes zoster infection. Presented.. Read More
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Hypoglycemia in Elderly Type 2 Diabetes Patients
Hypoglycemia is a condition of reduced blood glucose level below 70 mg/dl (3.9 mmol/l). Hypoglycemic coma is a medical emergency which usually associated with glycemia around 20 mg/dl (1.1 mmol/l). Prolonged severe hypoglycemia may result in permanent neurological disorders. Hypoglycemia also has a negative impact on the cardiov.. Read More
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Background: Point of Care (POC) capillary blood glucose measurement in diabetes patients in the primary care setting has been used in out-patient settings for many years; however, there were no published studies on the clinical impact of this practice. Aim: To evaluate the clinical impact of Point of Care (POC) capillary blood g.. Read More
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Cellular, Molecular and Therapeutic Advances in Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM) is an ancient disease, discussed 3500 years ago in literature. Vast population worldwide is suffering from this disease and yet it is found to be untreatable. As per WHO statistics 2012, the number of deaths in the world due to T2DM almost reached to 1.5 million. The number of people suffering fro.. Read More
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Diabetes and other Non-Communicable Diseases (NCD) are public health concerns in both developed and developing countries. Brazil and Japan have made publically available National Health Surveys focus also in the prevalence of NCD, among them Diabetes, Hypertension and Dyslipidemia. This study offers a unique opportunity to under.. Read More
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Incretin-Based Therapies and Cancer Risk: A Review of Recent Literature Safety Data
Type 2 diabetes mellitus represents almost 90–95% of all diabetes. In 2006 and in 2007, the pharmacological treatment of type 2 diabetes mellitus changed due to the introduction on the European market of the first GLP-1 receptor agonist, exenatide, and the first inhibitor of DPP-4, sitagliptin. These drugs act throughout t.. Read More
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Diabetic Patients Fasting During Ramadan: Ten Years Overview
Aim: Many diabetic patients insist on fasting in Ramadan despite the potential risks of hypoglycemia, hyperglycemia, diabetic ketoacidosis and diabetic hyperosmolar coma. These patients represent a challenge not only for themselves, but also for the professional care providers during this period that lasts a full month. Aim of t.. Read More
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