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Na/K-ATPase Oxidant Amplification Loop Regulates Cellular Senescence
As Na/K-ATPase oxidant amplification loop (NKAL) has been implicated in several diseases and oxidant injury plays a pivotal role in aging, we examined the effect of NKAL in the molecular pathogenesis of senescence. First, C57BL6 old mice were supplemented with a western diet to induce oxidant injury and pNaKtide was used to anta.. Read More
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Liver Involvement is Frequently Found in Patients with Primary Sjogrenâs Syndrome
There may be liver involvement in primary Sjogren’s syndrome patients. Our objectives were to correlate the presence of abnormal hepatic biochemistries with other clinical and laboratory features in patients with primary Sjogren’s syndrome and to determine the prevalence of clinical liver disease. Methods: The study.. Read More
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Exploring Seipin: From Biochemistry to Bioinformatics Predictions
The BSCL2 gene encodes seipin, a nonenzymatic protein. It is involved in the disorders lipodystrophy and seipinopathy. All seipin functions, which were named in 2001, are still poorly understood. As a result, we analysed a large amount of research in search of a pattern that could explain widely reported aspects of seipin expres.. Read More
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Review of the Clinical, Biochemical, and Metabolic Benefits
It is now understood that thiamin, generally known as vitamin B1, is essential for the metabolism of energy. It was found as a result of the initial research on the “anti-beriberi factor” present in rice polishing. It took years of investigation after its 1936 synthesis to determine how it worked to treat beriberi, a.. Read More
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Jordanian Doctors' Perspectives on Biochemistry and Genetics
According to a number of researches, doctors tend to harbor unfavorable views of the fields of genetics and biochemistry. A lot of medical schools use a system-based integrated curriculum that is augmented by clinical linkages. Jordan’s medical schools transitioned to an integrated curriculum, but there aren’t any st.. Read More
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Urinary Biochemistry is Used in the Diagnosis of Acute Kidney Injury
Acute kidney damage is a clinical illness that complicates and affects the course of a large number of hospitalized patients. Recent breakthroughs in clinical and basic research will aid in the characterization of this condition and the understanding of its pathophysiology. With this information, we will be able to perform more .. Read More
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Integrating Analytical Biochemistry, Biology, and Informatics
The newest of these sciences, metabolomics, combines analytical biochemistry to evaluate the metabolic complement with sophisticated informatics, bioinformatics, and statistics. Because the chemistry of metabolites is variable, several analytical techniques must be used for their extraction, separation, detection, and quantifica.. Read More
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Evaluation of Analytical Biochemistry by Aptamer Applications
Aptamers are single-stranded molecules of relatively short DNA or RNA (20–60 nucleotides) that bind to a variety of targets with high affinity and specificity. Aptamers are frequently referred to as “synthetic antibodies,” despite the fact that they are simpler to acquire, less costly to manufacture, and more v.. Read More
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A Review on the Post-Mortem Forensic Toxicology
One of the most important aspects of a successful forensic toxicological analysis is using an accurate and efficient extraction method on the post-mortem samples. Numerous successful attempts to effectively extract poisons from post-mortem samples have been made as science has advanced. The scientific conclusions and the legal v.. Read More
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Effects of Anthropogenic Habitat on Plasma Biochemistry of Urban- Breeding Ring-Billed Gulls
Gulls (Larids) have mastered the art of foraging in human-created areas. However, little is known about the health effects of using anthropogenic habitats and the exposure to environmental pollutants that comes with it. This is especially true when it comes to plasma biochemistry, which is frequently used to diagnose physiologic.. Read More
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A Review on the Membrane Protein Biochemistry Applications
The predictive powerhouse of protein structure and function that is protein sequence coevolution analysis has recently matured. The prediction of membrane and disordered protein structures, protein complex architectures, and the functional effects of protein mutations have been made possible by direct methods that make use of gl.. Read More
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Introduction: Vitamin B12 and Folic acid (FA) deficiency is considered as a public health problem. The reasons for this condition are the varying dietary habits. The main reasons for vitamin B12 and FA deficiency are nutritional deficiencies. Vitamin B12 is also called as Cyanocobalamine. It is essential in enzymatic reactions l.. Read More
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The extraction of Biological matrices by FPSE-GC-MS technique
During the pandemic emergency in 2020, favipiravir, a pyrazine analog, is proposed as a providential antiviral agent against the COVID-19 infection. Fabric phase sorptive extraction (FPSE) and gas chromatography-mass spectrometry (GC-MS) have been developed and used for the first time to identify favipiravir (FAV) in pharmaceuti.. Read More
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Isolation of a Bacterial Lanthanide and Pyrroloquinoline Quinone by Methanol Dehydrogenase
The cell biology of metals is relatively new to the field of lanthanides; their particular fuse into chemicals was just exhibited in 2011, with the confinement of a bacterial lanthanide-and pyrroloquinoline quinone-subordinate methanol dehydrogenase. Numerous research efforts have since been focused on elucidating the molecular .. Read More
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A Review on the Chemical Production by Cell-Free Approach
The maintenance of life processes frequently runs counter to our desire to maximize important production metrics, which presents inherent difficulties for metabolic engineering efforts that harness living organisms to produce natural products and other useful chemicals. For commodity chemical manufacturing, where cost is of the .. Read More
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A Review on the Cysteine Synthase
The Cysteine Synthase (CS) enzyme, which is responsible for the synthesis of cysteine, plays non-canonical regulatory roles by binding to and altering the functions of various proteins. By binding to a small number of other proteins that have a C-terminal “CS-binding motif” that ends in a terminal ILE, it performs it.. Read More
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A Review on the Mitochondrial Protein Function
In the post-genomic era, it is essential for our comprehension of basic biology and disease pathogenesis to define functions for the entire protein family. This endeavor has recently benefited from a process we refer to as “systems biochemistry” that helps overcome traditional barriers to the characterization of poor.. Read More
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An Overview on Serum Biochemistry and Lipid Oxidative Stability
The study consider examined the impacts of Lactobacillus acidophilus (LBA) and manna-oligosaccharides (MOS) supplementation on the generation execution, serum natural chemistry, antioxidant profile, wellbeing lists, meat quality, and lipid oxidative soundness of broiler chicken. A add up to of 252 commercial broiler chickens at .. Read More
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The Biochemistry of Organic Residues Controls Soil Nutrient Cycle and Energy Production
One of the most crucial elements affecting the breakdown of plant leftovers in soils is substrate composition. In a laboratory experiment, the relationship between organic residue biochemistry and rates of decomposition, soil aggregation, and soil humus composition was discovered. When seven distinct organic residues were added .. Read More
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A Review on Forensic Entomology during Covid 19
As the COVID-19 pandemic overturned college and college instruction throughout the world, instructors were hard-pressed to discover suitable alternatives for viable exercises typically carried out exterior of classrooms—in laboratories, workshops, clinics, and within the field. In response to this unanticipated challenge, .. Read More
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