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Octreotide Labelled Fluorescein Isothiocyanate for Identification of Somatostatin Receptor Subtype 2
Cancer can be detected by certain signs and symptoms, it is can be investigated by medical imaging and confirmed by biopsy. Many tumor cells express some kind of receptor, e.g., somatostatin receptors. Somatostatin receptor-positive human tumors can be detected using labeled analogues of somatostatin. In vitro labeled octreotide.. Read More
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Physiological Role of Endocannabinoid-Hydrolyzing Enzymes in Brain Development and Neurodegeneration
Endocannabinoids (eCBs) such as 2-arachidonoylglycerol (2-AG) and N-arachidonoylethanolamide (AEA) are important lipophilic mediators for transducing in signals organizing neuronal wiring in brain development, tuning retrograde signaling during synaptic transmission, or regulating neuroinflammation. e-CB hydrolyzing enzymes such.. Read More
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A Fine-Tuned Management between Physiology and Immunity Maintains the Gut Microbiota in Insects
The association of microbial community with the digestive system is a distinct phenomenon and the insect gut is an excellent model to understand these interactions. Insects are omnivorous, feed on all kinds of food and encounter a variety of microbes. The diversity of these large and varied microbial communities inhabiting the g.. Read More
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Introduction: In an era where mechanization of laboratory automation has drastically reduced the errors due to the analytical phase of testing, errors due to the preanalytical phase are largely responsible for the decrease in quality of clinical laboratory results. Materials and methods: The present study was conducted at one o.. Read More
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OPG Expression on Endothelial Cells and Modulation by IL-1B, PDGF, Insulin, and Glucose
Introduction: Osteoprotegerin (OPG), an osteoclastogenesis inhibitor implicated in bone remodelling, has emerged as a potential biomarker for cardiovascular diseases. However, OPG circulating sources or the stimuli that increase its release and effects have not been established. Objective: The aim of the present study are to es.. Read More
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Background: Enzymes play a very important and central role in the chemical reactions, occurring in biological systems. The study of enzymes has an immense practical importance. They have high catalytic power, many times greater than the synthetic catalysts. Vascular blockage can cause serious consequences leading to death by a t.. Read More
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In this study the interactions of Riboflavin (Vitamin B2) with a mercury surface are investigated. Firstly, by using Cyclic Voltammetry, it is demonstrated that Riboflavin can be efficiently accumulated, by adsorption from buffered solutions containing an excess of NaClO4, onto the mercury drop of a HMDE. Secondly, it is shown t.. Read More
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The Ultrasonic velocity, Densities, viscosities, refractive index and Surface tension have been measured for binary mixture of Benzylparaben with Benzene at temperatures T=303.15, 308.15 and 313.15 K at different molefractions such as 0.1 to 1.0. The experimental data have been used to calculate the acoustical and thermodynamica.. Read More
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Current Perspective on Hydrogen Sulfide: Stinky Outside Precious Inside
Hydrogen sulfide is the newest member of gasotransmitter family. Endogenous production of hydrogen sulfide in brain was first reported in 1996. Since then a great deal of interest has been paid to understand various physiological roles of this molecule, still there are a lot of gaps that need to be addressed. This article provid.. Read More
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Effect of Ormeloxifene for Management of Dysfunctional Uterine Bleeding
Menorrhagia is an abnormal vaginal bleeding. Ormeloxifene is anti proliferative drugs which reduce production of various endometrial derived local factors and corrects menorrhagia with decrease menstrual blood loss (MBL) and clots. Therefore, we aimed to determine the effect of Ormeloxifene in women with dysfunctional uterine bl.. Read More
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Surfactant Assistant Enhancement of Bioremediation Rate for Hexavalent Chromium by Water Algae
Cr(VI) in waste water is a serious pollutant in diverse environmental conditions due to its toxicity and carcinogenicity. Bioremediation can alternatively be used to the conventional chemical treatments. Bioremediation of toxic hexavalent chromium is done by reduction of hexavalent chromium to nontoxic trivalent chromium in cons.. Read More
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Phytoextraction: Using Brassica as a Hyper Accumulator
Phytoextraction is a cost-effective method that could be an alternative to remediate polluted sites. Growth performance, biochemical, enzymatic activity, accumulation, translocation and mobility of arsenic form soil to root and leaves were studied in co-cultivated hyper accumulator (Brassica juncea) and hypo accumulator (Abelmus.. Read More
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Aim: The study was carried out to investigate effects of administration ethanol leaf extract of Gongronema latifolium and Piper guineense on lipid profile parameters against ethanol – induced hepatic injury in rats. Method: Forty male albino rats (weighing 150-220 g) were used. The animals were divided into four groups A,.. Read More
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Prenatal Testosterone Exposure Influences Neuronal Sensitivity to Pheromones in Female Mice
Exposure to androgens during in utero development in animals which give birth to multiple offspring causes lifelong increased sensitivity in the offspring. Females who develop with a male on each side (designated 2M) are exposed to the testosterone produced by these males due to the steroids freely crossing cell membranes. Femal.. Read More
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Assessment of Toxic Activity of Heat Labile Toxin from Bordetella pertussis Vaccine Strain 134
Heat Labile toxin (HLT) is a mouse lethal toxin produced by all virulent Bordetella pertussis species. B. pertussis cells were dermo necrotizing and lethal when injected in to animals. Therefore in the present study the biological property of heat labile toxin of B. pertussis strain 134 was assessed before and after heat inactiv.. Read More
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Alterations In Salivary Gland Secretion And Contemporary Treatment Alternatives
Saliva is a significant secretion in the preservation of oral cavity, preparation of food for chewing and swallowing, remineralization of teeth, neutralization of oral acid and simplification of speech. Decrease or increase of this secretion can cause various oral and general health problems. While hyposalivation leads to xerost.. Read More
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Teak (Tectona grandis L.) is amongst the precious tropical trees produces luxurious wood items and metabolites of great medicinal value. However, teak growth is hampered due to high dormancy and poor viability of the seeds under the normal field conditions. Here we investigated the effect of various cytokinins on seed germinatio.. Read More
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An Overview on Wounds Their Issues and Natural Remedies for Wound Healing
In the present review, new and necessary information about wounds, their healing stages and concerned issues; hydrogel wound dressing and their cross linking systems which affect the wound healing are discussed. However, concerns associated with the overuse of synthetic drugs and the consequent emergence of bacterial resistance .. Read More
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The Potential of Cyanobacteria Growth in Different Water Sources
Many studies have addressed the effect of different environmental factors on growth, heterocyst frequency and N fixation of cyanobacteria. One of the factors is water quality. Different cyanobacteria strains different efficiency to adapt the quality of water. Therefore, this study was conducted to select the best combination of .. Read More
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Doxorubicin (DOX) is an effective antineoplastic agent widely used for the treatment of various cancers; however, its clinical use is limited due the induction of dose-dependent toxicity in the hearts of patients receiving this drug. Therefore any agent that can reduce its myocardial toxicity will be very useful in clinics. The .. Read More
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