Human adipose tissue is composed of fat derived from lipoblasts. The amount of fat is associated with obesity in humans. Human adipose tissues store energy and produce several hormones and cytokines such as insulin, adiponectin, leptin, resistin, interleukins, and tumor necrosis factor (TNF)-alpha. There are also several types of cells in human adipose tissue, such as multipotent adipose stem cells, adipose stromal cells, and adipocytes. Adipose stem cells can differentiate into adipogenic, chondrogenic, and osteogenic cells. Because of these characteristics, adipose tissue has been used clinically not only as a source of adult stem cells but also as biomaterial for tissue engineering. Adipose tissue derived-cells were isolated by two different methods, mechanical (chopping) or enzyme treatment (collagenase).
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Last date updated on August, 2022