|Cyclooxygenase (COX) is an essential enzyme in the formation of prostaglandins, prostacyclin and thromboxane which are major biological mediators. The symptoms of swelling and pain are relieved by inhibitting COX. Aspirin and ibuprofen are the non-steroidal anti-inflammatory drugs which show their action through inhibition of COX.Scholarly peer review is the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts in the same field, before a paper describing this work is published in a journal. The work may be accepted, considered acceptable with revisions, or rejected. Peer review requires a community of experts in a given (narrowly defined) field, who are qualified and able to perform reasonably impartial review.