|Platelet-activating factor (PAF) is a potent phospholipid activator of g-protein coupled receptor. It also acts as as a mediator of biological functions such as platelet aggregation and degranulation, inflammation, and anaphylaxis at very low concentrations. It is also responsible for changes in vascular permeability and chemotaxis and oxidative burst of leukocytes.A journalÂ is aÂ periodical publicationÂ intended to further progress ofÂ science, usually by reporting newÂ research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, andÂ scientific papersÂ across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientificÂ validity. Each such journal article becomes part of the permanent scientific record.