The Bio-implantable artificial kidney device in the world was first invented by Indian Bioengineering specialist Shuvo Roy and his team in the University of California. This first artificial kidney can imitate most of the key functions of the kidney. It filters toxins, performs all the metabolic and hormonal functions of a normal kidney. But the device complete animal trails and is in the stage of human trials, which on completion successfully can possibly replace the kidney dialysis and transplant. This device is in the size of a coffee cup and has 2 components- filter and cellular side. The first part is made up of silicon chips and helps in filtering of toxins from the bloodstream. Then filtered blood is pumped into the second part of the device which is also made up of silicon chips and is coated with a single type of human kidney cells. These renal cells help to reabsorb some of the water, sugar and salt back into the body, produce vitamin D and regulate the blood pressure. The waste products are directed through a tube that is attached to the urinary bladder and then excreted as urine. Patients may not require anti-rejection drugs - as is required after transplants as there would be no exposed natural tissues for the immune system to attack. Animal trials have shown good results so far and human trials will be conducted over the next five to seven years. Hope invention of Dr. Roy is successful in Human trails and the device resolves the several chronic kidney diseases and specifically patients with lifelong Dialysis.
For more study check at https://www.omicsonline.org/nephrology-therapeutics/chronic-kidney-disease-news.php