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Heat shock proteins (HSPs) are ubiquitous which can be seen in all organisms and in different sub cellular compartments, their predominant function being the folding and unfolding of protein substrates. From the immunological point of view, HSPs have been concerned in stimulation of the innate and adaptive immune systems. The ability of HSPs to bind antigenic peptides and deliver them to APCs forms the basis for their potential role in the generation of peptide-specific T lymphocyte responses.
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