We have concerned ourselves at the gastroenterology unit of the VU University Medical Center with drug repositioning since 2001. Generic therapy, often successfully used off-label in daily practice and well described in literature in large observational studies, should be further developed for safe and economically viable use. To prevent off-label use legislative authoritiesshouldstimulate re-registration of these drugs.
Citation: Mulder CJJ, Asseldonk DPV, de Boer NK (2015) Drug Rediscovery: Preventing Off-label Prescription and Reducing Health Care Costs: The Case of Thioguanine in the Netherlands. J Gastrointest Dig Syst 5:249. doi: 10.4172/2161-069X.1000249