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Tablets must be able to withstand mechanical stresses during their manufacturing, distribution and handling by the end-user. Does your tablet remain intact during coating, packaging and printing processes? Is your tablet broken when the patient accidently drops it onto the floor? Both friability and hardness measure the mechanical integrity of tablets.Friability is a measure of the resistance of the tablets to shipping and abrasion by tumbling them in a rotating drum. After tumbling, the integrity of the tablets and the weight loss are evaluated. Anabiotec has a Sotax F1 friability tester. With this equipment it is possible to measure in two modes: a specific time interval or a specified number of rotations.
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