alexa Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity

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Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity

The promise of 'personalized cancer care' with therapies toward specific molecular aberrations has potential to improve outcomes. However, there is recognized heterogeneity within any given tumor-type from patient to patient and within an individual as demonstrated by molecular evolution through space and time. These issues have become hurdles to advancing cancer treatment outcomes with novel molecularly targeted agents.

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