The impact on society of successful translation of a basic or clinical observation into new therapies is substantial taking into the consideration rapid growth of scientific knowledge. Today, understanding and meeting public concerns are as important for the investigator as performing research studies. As science moves forward the issue of communicating new data to the society poses special challenges to the investigator. These challenges create needs to complement traditional academic publishing by launching free, on line journals, many of them open access and peer-reviewed. The Journal of Autacoids, is an international, peer-reviewed journal that overlays different aspects of biomedical science relevant to biological factors which are being formed by the tissues on which they act; thus they function as local hormones produced by many tissues.