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In silico Prediction of the Blood-Brain Barrier Permeation: Are We There Yet?

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In silico Prediction of the Blood-Brain Barrier Permeation: Are We There Yet?

The drug discovery and development has turned to a new chapter ever since the implementation of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) in the United States of America and Human Brain Project (HBP) in the European Union. Both initiatives have signified the imminence of finding the treatment for the central nervous system (CNS) disorders such as Alzheimer's disease (AD), Parkinson’s disease (PD), brain cancer, and stroke, which, in turn, are substantially affected by aging. Nevertheless, the average lifespan of people increases gradually, resulting in the fact that more and more people are now living with AD, and, more practically, the health care for the CNS diseases will become substantially financial burdens around the globe.

Citation: Leong MK (2015) In silico Prediction of the Blood-Brain Barrier Permeation: Are We There Yet? Med chem 5:130-130. doi:10.4172/2161-0444.1000254

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