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This paper reports on the construction and predictive models of the Ion Channel Switch (ICS) biosensor which is capable of detecting femto-molar concentrations of target species including proteins, hormones, polypeptides, microorganisms, oligonucleotides, DNA segments, and polymers in cluttered electrolyte environments. The ICS employs an engineered tethered membrane with embedded gramicidin (gA) monomers and tethered antibody receptors.
Citation: Hoiles W, Krishnamurthy V, Cornell B (2014) Membrane Bound Molecular Machines for Sensing. J Anal Bioanal Tech S7:014. doi:10.4172/2155-9872.S7-014
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