Wilms tumor is a solid cancerous tumor of the kidney that arises from immature kidney cells. Generally occurs in children with WAGR syndrome, Denys-Drash syndrome and Beckwith-Wiedemann syndrome. Wilms tumor is the fourth most common type of childhood cancer and the most common type of kidney cancer in children.
Symptoms of Wilms tumor include: Hardness or swelling in the abdomen, Fever, Nausea, Loss of appetite, Blood in the urine, Constipation and hypertension.
Wilms tumor is treated by Surgery, Chemotherapy and Radiation therapy.
The risk for developing Wilms tumor is higher in African Americans than Caucasians, and lower among Asians. Children with one kidney affected (unilateral) are usually diagnosed around 3 years of age. Children with bilateral Wilms tumor are usually diagnosed around 2 years of age.