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Therefore, toxic pathology study has as compelling scientific role in evaluating product, which characterizes responses in tissue and distinguish optimal help as regeneration from deficient or partial outputs which is an indicative of substandard functionality to repair. As new-tissue engineering and regenerative medical technologies develop for tissue and organ regeneration, the toxic pathologist will be asked to develop novel testing, to reevaluate established toxic diagnostic criteria and reinterpret tissue responses that may extend beyond present standards.