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In developed countries, the morbidity and mortality in Human Immunodeficiency Virus (HIV) patients is significantly induced by chronic Hepatitis C Virus (HCV) co-infection. It is estimated to have about one-third of HIV patients co-infected with HCV. These patients usually require immediate HCV treatment as they tolerate poorly towards antiretroviral treatment, progress more rapidly to end-stage liver disease and often lead to death.
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