alexa Role of Heat Shock Protein Derived from Streptococcus sanguinis

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Role of Heat Shock Protein Derived from Streptococcus sanguinis

Patients with Behcet’s disease (BD) have hypersensitivity against oral streptococci increased in their oral cavity. Heat shock protein-65/60 (Hsp-65/60) derived from S. sanguinis and the damaged mammalian tissues, respectively, are supposed to play an important role in BD pathogenesis. The antigen presenting cells taken Hsp-65 via Toll-like receptors in the oral lesion are carried to the local lesions by blood flow and they are known to lead T cells undergo apoptosis in the regional delayed type hypersensitive reaction.

Citation: Kaneko F, Togashi A, Nomura E, Nakamura K, Isogai E, et al. (2012) Role of Heat Shock Protein Derived from Streptococcus sanguinis in Behcet’s Disease. J Medical Microbiol Diagnosis

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