alexa Ageing and Cancer

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Ageing and Cancer

Ageing and cancer share some common biology. Genomewide examinations show that overlapping genes between them can be classified into functional categories and pathways, e.g., cell cycle regulation, metabolic processes, DNA damage response, apoptosis, the P53 signalling and chemokine signalling pathway, and the immune/inflammatory response . Currently, both the cause-effects “mutation” theory of cancer and the free radical theory of ageing are under question. The former has difficulty explaining how cancers arise, and why conventional chemotherapy succeeds or fails . Similarly, the idea that the macromolecular damage from toxic reactive oxygen species is the cause of ageing now faces challenges from evidences regarding the rival mTOR-centric model .

Citation: Zhang Y (2013) Ageing and Cancer: Breaking the “Dont Put All Eggs in One basket” and Natural “Self-organisation”, and their Potential Reprogramming via Modulation of Mi-2/NuRD, mTOR Kinase and Metabolism

  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger