A study of 24,149 patients who developed chronic kidney disease between 2001 and 2008 were noticed and One out of four of the kidney patients had been previously treated using a PPI. Patients taking a PPI also had an increased risk of dying prematurely, the researchers found. The same findings were seen in other study wherein the team followed 10,482 adults with normal kidney function from 1996 to 2011. They found that PPI users were up to 50% more likely to develop chronic kidney disease than non-PPI users, even after adjusting for differences between the two groups.
However, the findings from the studies are scheduled to be presented next week at the American Society of Nephrology's Kidney Week 2015, held from Nov. 3 to 8 in San Diego.