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Progression of chronic kidney disease (CKD) from stage 3 to stage 4 is associated with significantly increased risks of death, acute kidney injury, and hospitalization prior to development of end-stage renal disease (ESRD), a new study suggests.
The researchers defined CKD stage 3 as an estimated glomerular filtration rate (eGFR) of 30–59 mL/min/1.73 m2). They defined progression to CKD stage 4 as 2 independent outpatient eGFR values less than 30 mL/min/1.73 m2.