alexa A Crosstalk and Stress Exchange Beyond the Gut hypothesis

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A Crosstalk and Stress Exchange Beyond the Gut hypothesis

For many decades, the consequences of “stress” have been perceived as a “unidirectional” pathway where some stressful life conditions cause “mental stress” that activates the brain’s stress response systems, which sequentially affect many of the major body systems especially gastrointestinal tract. The striking upsurge in incidence of neuropsychiatric and neurodevelopmental disorders, in the last five decades, appeals to a crucial “bidirectional” interaction between the nervous system with other body systems. Such fast expansion of these disorders enforces also a causal role for environmental insults inflicted by the changing ecosystems as well as the modernization of human life style including lavish use of antibiotics, high hygiene standards and predominant utilization of urban western diet.... read more

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