Chromatin is subject to proofreading and repair mechanisms during the process of DNA replication, as well as repair to maintain genetic and epigenetic information and genome stability. The dynamic structure of chromatin modulates various nuclear processes, including transcription and replication, by altering the accessibility of the DNA to regulatory factors. Structural changes in chromatin are affected by the chemical modification of histone proteins and DNA, remodeling of nucleosomes, incorporation of variant histones, noncoding RNAs, and non-histone DNA binding proteins. Phenotypic diversity and fidelity can be balanced by controlling stochastic switching of chromatin structure and dynamics in response to the environmental disruptors and endogenous stresses.
OMICS is one such organization which freely publishes online journals where quality information resides and students, academicians etc can improve their knowledge by freely accessing these journals. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals. Molecular Biology is one of the best online open access journals which publish original research, review, Short communication, and Case study in the field of Molecular Biology and its current research. It has world quality editorial board members in order to develop its standards.
Last date updated on July, 2014