Chromatin is subject to proofreading and repair mechanisms during the process of DNA replication, as well as repair to maintain genetic and epigenetic information and genome stability. The dynamic structure of chromatin modulates various nuclear processes, including transcription and replication, by altering the accessibility of the DNA to regulatory factors. Structural changes in chromatin are affected by the chemical modification of histone proteins and DNA, remodeling of nucleosomes, incorporation of variant histones, noncoding RNAs, and non-histone DNA binding proteins. Phenotypic diversity and fidelity can be balanced by controlling stochastic switching of chromatin structure and dynamics in response to the environmental disruptors and endogenous stresses. Only a very few journals maintain high standards in terms of the content they publish, one has to be careful while picking information as content that is not reliable and untrue can be harmful to research as well as society. Generally, journals can be rated by considering impact factor, reputation of authors, editorial board members and also in terms of the fee they charge. Only high indexing journals have quality articles. Molecular Biology is one of the best journals which publish quality articles. Molecular Biology is a wide range of area that deals with different aspects. It publishes original research, review, short communication, case report, mini review etc.
Last date updated on July, 2014