Chromatin is subject to proofreading and repair mechanisms during the process of DNA replication, as well as repair to maintain genetic and epigenetic information and genome stability. The dynamic structure of chromatin modulates various nuclear processes, including transcription and replication, by altering the accessibility of the DNA to regulatory factors. Structural changes in chromatin are affected by the chemical modification of histone proteins and DNA, remodeling of nucleosomes, incorporation of variant histones, noncoding RNAs, and non-histone DNA binding proteins. Phenotypic diversity and fidelity can be balanced by controlling stochastic switching of chromatin structure and dynamics in response to the environmental disruptors and endogenous stresses.
Discovery and research are never ending process; man always tries to find something new for his advancement. Journals are the means of disseminating research findings. They help the common man to explore the discovery made by scholars. Journals play a very important role in maintaining periodical record of events and help us in collecting information and thus streamlining our knowledge. Generally, journals refer to collection of Scholarly articles that are published regularly and are peer reviewed. As its peer reviewed it enhances the collaborative efforts from scholars. Internationally published journals accelerate scientific research by increasing quality, competency and credibility. They increase the performance of each and every scholar there by contributing a lot to scientific community. Molecular Biology is one of the best reputed journals which publish original research, review, Short communication, Case study in the field of Molecular Biology.
Last date updated on July, 2014