Endocrinology Review Journals | OMICS International | Endocrinology And Metabolic Syndrome

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Endocrinology Review Journals

There exists a correlation between obesity and inflammatory markers, such as C-reactive protein (CRP), which has been associated with increased risk of cardiovascular disease (CVD). Levels of CRP are influenced by different factors such as obesity, smoking, alcohol, physical activity, and genetics. CRP through systemic inflammation could well be the connecting link between obesity, insulin resistance, and CVD. Future research should be directed to answer whether CRP plays any major biological role in metabolic syndrome or is just a marker. Focus should be on systems-based approaches that combine genomic, molecular and physiological data to understand the complexity of metabolic syndrome. Some studies have suggested that the disruption of the circadian rhythm (chronodisruption) may lead to metabolic syndrome. Animal models such as mice have revealed that disruption of genes regulating circadian clock results in a phenotype similar to metabolic syndrome. Interestingly, studies in humans have shown that genes influencing circadian rhythm are expressed in adipose tissue, and that their expression levels and genetic variants correlate with different components of the metabolic syndrome. It would be intriguing to study the relationship between polymorphisms in different circadian genes and traits associated with metabolic syndrome. I am sure the journal “Endocrinology and Metabolic Syndrome” from OMICS Group will make a positive impact in this direction. Metabolic Syndrome: The Genetic Aspect: Vijaya Krishna Varanasi
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Last date updated on April, 2021