The glucose metabolism is altered in the people with diabetes. In type 2 diabetes, the effectiveness of insulin is reduced and in type 1 diabetes, insulin levels in the body are low as the pancreatic beta cells stop producing insulin. Metabolic syndrome and type 2 diabetes, impairs the bodyâs ability to use glucose. As a result blood sugars levels increases, weight gain is more expected and the resistance to insulin becomes greater. Glucose production is increased in people with type 2 diabetes before and after food intake. Excessive glucose production occurs due to delayed insulin secretion and lack of suppression of glucagon release. Regulation of hepatic glucose metabolism in type 2 diabetes will require normalization of insulin and glucagon secretion as well as hepatic insulin action. In type 1 diabetes, the patients are administered with regular insulin for the glucose metabolism.
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2014