Non-motor symptoms of Parkinsonââ¬â¢s disease (PD) have received increasingly more recognition in recent years. Pain is among such non-motor sensory disorders and occurs frequently in patients with PD. Although chronic pain among patients with PD can be caused by motor symptoms, it has also been reported independently of these symptoms. relationship between cognitive dysfunction and non-motor symptoms in patients with PD has shown that sleep disturbances in this group may be an early marker of dementia. It has also been reported that PD patients have decreased circulating helper T cells (CD4+), while cytotoxic T cells (CD8+) are unchanged or slightly increased relative to controls.
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Last date updated on September, 2024