|The therapy which involves the altering of genes in the body inorder to stop the diseases is known as Gene Therapy. This therapy is mostly used in the diseases like cystic fibrosis, AIDS, Heart Diseases. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information.