Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas. Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don't know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.
Abnormal hair development and regeneration occurs in some skin diseases, including lymphomas when hair follicles are eliminated. Otherwise, neoplastic cells, both malignant and benign, local occurring and metastatic, can cause alopecia of the scalp. In lymphomas alopecia can develop due to direct infiltration by the disease, or it may be a secondary or paraneoplastic manifestation. Total -body hair loss can be diagnosed only in those with generalized erythroderma in mycosis fungoides and SÃ©zary syndrome. Patchy alopecia clinically identical to alopecia areata is revealed in 34% patients suffering from mycosis fungoides or SÃ©zary syndrome. Discreet patch/plaque or follicular lesions is observed within mycosis fungoides lesions in 66%. The involvement of hair follicles usually presents in folliculotropic mycosis fungoides. 65% of patients have alopecia. Follicular mucinosis is frequent in folliculotropic mycosis fungoides. Alopecia is also observed in ichthyosiform mycosis fungoides, syringotropic cutaneous T-cell lymphoma panniculitis-like T-cell lymphoma, primary cutaneous follicle center lymphoma Occipital alopecia areata, occipital and parietal alopecia were observed in B- cell lymphoma. Alopecia is a rare manifestation of Hodgkinâs disease. Alopecia may develop due to therapy and can be even a sign of therapeutical efficacy.
Citation: Khamaganova I, Khromova S, Shvec O (2014) Alopecia in Lymphomas. Hair Ther Transplant 4:117. doi: 10.4172/2167-0951.1000117
Last date updated on July, 2014