Non-viral vectors, such as cationic polymers, peptides, and liposomes, have attracted interest because of their advantages compared to viral systems. For example, research suggests that non-viral vectors are safer, with more flexible structures and chemical properties. Among the various types of polymer gene carriers, branched polyethylenimine (B-PEI) is the most effective vector for delivering genes because the BPEI/DNA polyplexes exhibit great transgene expression in vitro and in vivo.
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Last date updated on November, 2020