Protein therapeutics holds significant promise for improving human health. Our organism contains thousands of proteins, which perform essential functions in growth, development and metabolism regulation. Many diseases arise from the alterations in the functions of intracellular proteins. Therefore, the administration of therapeutic proteins has shown great potential in the treatment of many diseases, including cancer and diabetes. Protein therapeutics has emerged since the 1980s and represents currently a significant part of biopharmaceuticals. For example, LantusÂ®, an engineered protein (insulin) was one of the top ten selling biopharmaceuticals in 2009. Moreover, protein drugs with much better therapeutic performance are developed every year. The pharmaceutical research and manufacturers of America (PHRMA) listed 78 therapeutic proteins in 813 new biotechnology medicines related to more than 100 diseases in 2011, including virus infectious, cancer and autoimmune diseases.
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Last date updated on July, 2014