Poly (vinyl alcohol) (PVA) is a semi-crystalline synthetic polymer with good mechanical properties, that proved biocompatible. These characteristics make this hydrogel particularly suitable for pharmaceutical, biomedical, and cosmetic applications. Its structure presents some features that make it an excellent candidate for biomaterial synthesis. In fact it is non-toxic, non-carcinogenic, easy to be processed and bioadhesive. PVA is produced by the polymerization of vinyl acetate to poly (vinyl acetate), followed by hydrolysis of PVAc to PVA. The molecular weight distribution, the degree of deacetylation and the initial concentration of PVA are the main parameters that affect hydrogel properties such as crystallizability, adhesion, mechanical strength, and diffusivity.
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Last date updated on July, 2014