For the survival and normal functioning of a cell and ultimately of the whole organism, conservation and protection of the native DNA sequence and structure is necessary. However, our bodies are constantly exposed to diverse types of genotoxic insults from various sources that can damage cellular DNA and threaten the survival. In order to maintain genomic integrity, eukaryotic Cells have developed intricate DNA damage sensing and repair mechanism that combats the diverse sources of DNA damage and ensures survival. The signalling responses that are triggered following DNA damage from endogenous or exogenous sources give rise to a pathway called DNA Damage Response (DDR) pathway. The DDR pathway has evolved to be a complex, yet sensitive, highly integrated and interconnected pathway.
OMICS group encourages innovation in research field/scientific community. The published articles in OMICS journals include most of the trending topics. Molecular Biology has a very vast scope and covers all aspects in molecular sciences. Molecular biology journal publishes current research topics.
Last date updated on July, 2014