alexa Colonic Medullary Carcinoma is Unique and Important to Recognize

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Colonic Medullary Carcinoma is Unique and Important to Recognize

Adenocarcinoma of the colon is a common and well-recognized entity, and is the third most common type of cancer worldwide. In the United States, it was the second leading cause of death from cancer in 2007. Medullary carcinoma (MC) of the colon is a relatively new histological type of colon cancer and constitutes less than 1% of colorectal neoplasms. It was formerly known as ‘large cell adenocarcinoma with minimal differentiation’. MC is a rare subtype of poorly differentiated adenocarcinoma with very little glandular differentiation. It can be further subdivided into poorly-differentiated and undifferentiated MC. Although there is a tendency for large tumor size, lymph node involvement and distant metastasis are rare. It is essential to recognize this pathology, as studies suggest there is a trend toward a different disease course with MC, as compared to non-medullary poorly-differentiated adenocarcinoma (PDA) and undifferentiated adenocarcinoma (UDA). Herein, we present a case of an elderly male with rapid progression of MC.

Citation: Kim AH, Shellenberger JM, Mowery A (2014) Colonic Medullary Carcinoma is Unique and Important to Recognize. General Med 2:148. doi: 10.4172/2327-5146.1000148

 
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