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Cardiovascular autonomic neuropathy (CAN) is one of the most serious microvascular complications of Diabetes Mellitus (DM) and one of the most overlooked. CAN has been considered as an early subclinical feature of diabetic complications as it can occur one year of diagnosis in patients with poor controlled DM Type 2 and after two years of poor controlled DM Type 1, also. Furthermore, it has been associated with increased cardiovascular mortality and morbidity in many studies.
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