alexa Recombinant Factor VIIa

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Recombinant Factor VIIa

Background and Objectives: Recombinant factor VIIa (rFVIIa) is approved for treatment of inhibitors in hemophilia but has also been used for numerous off-label indications. Type of study: This study aims to validate a modified Biss scoring system in patients who received recombinant factor rFVIIa in Jeddah, Saudi Arabia. Materials and Methods: We included 70 patients who received rFVIIa for off-label indications over 12 months. Characteristics of survivor and non-survivor groups were compared including demographics, laboratory and clinical data. Using a modified Biss prognostic scoring system, based on the original scoring system used by Biss and Hanley, patients were divided into low (<1), intermediate (1-2) and high (≥3) score groups.


Citation: Zaher G, Adam S, Azher F, Hindawi S, Damanhouri G (2015) Validation of a Scoring System for Prediction of Clinical Outcome in the Off-label Use of Recombinant Factor VIIa. J Hematol Thrombo Dis S1:003. doi:10.4172/2329-8790.1000S1003

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