alexa Validation of a Scoring System for Prediction of Clinical Outcome in the Offlabel Use of Recombinant Factor VIIa

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Validation of a Scoring System for Prediction of Clinical Outcome in the Offlabel Use of Recombinant Factor VIIa

Recombinant activated factor VII (rFVIIa; NovoSeven, Novo Nordisk A/S, Bagsværd, Denmark) was specifically developed for use in hemophilia A and hemophilia B patients with corresponding factor inhibitors [1]. The Food and Drug Administration (FDA) approved rFVIIa in the United States in 1999 for management of bleeding episodes in patients with congenital hemophilia A or B with inhibitors (auto-antibodies to coagulation factors VIII and IX). The label was subsequently expanded to include patients with acquired hemophilia, congenital factor VII deficiencies and inherited platelet disorders.

 

Citation: Zaher G, Adam S, Azher F, Hindawi S, Damanhouri G (2015) Validation of a Scoring System for Prediction of Clinical Outcome in the Off-label Use of Recombinant Factor VIIa. J Hematol Thrombo Dis S1:003. doi:10.4172/2329-8790.1000S1003

 
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