alexa EAM as a New Conditioning Regimen for Lymphoma Patients

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EAM as a New Conditioning Regimen for Lymphoma Patients

Autologous progenitor cells transplantation (APCT) after a high dose conditioning chemotherapy is now an established treatment modality for many hematological malignancies such as lymphoma [1]. Clinical results and survival after APCT depend on disease chemo sensitivity at transplant and the efficacy of the conditioning regimen at eradicating the residual tumor cell clone [2]. The impact of the conditioning regimen is a controversial matter and despite efforts to identify high-dose regimens with increasing antitumor activity and acceptable toxicity to normal tissues, there is not yet clear evidence of a superior conditioning platform that should be applied in the setting of recurring lymphoma patients, at least in terms of tumor-eradicating capacity.

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