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The Lymphatic System: A New Focus on its Role in Metabolism and Metabolic Disorders

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The Lymphatic System: A New Focus on its Role in Metabolism and Metabolic Disorders

Lymphatic vessels not only play a physiological role in maintenance of homeostasis and the immune response together with blood vessels, but also participate in the development of pathological states such as inflammation and cancer metastasis [1]. In addition, mesenteric lymphatic vessels have a specific function, including absorption of long-chain fatty acids from the small intestine. Several recent studies have shown that the lymph circulation plays an important role in not only lipid metabolism [2] but also carbohydrate metabolism [3], and that morphological and functional impairment of the lymphatic system may be related to the pathophysiology of metabolic syndrome [4] and type 2 diabetes mellitus..

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