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Problem statement: Diabetes mellitus is a global public health problem with increasing prevalence. The purpose of this study was to investigate changes in some haematological parameters in patients with type 1 diabetes (T1D) in Sokoto, North Western Nigeria and to compare the results with non-diabetics. Material and methods: A total of 100 consecutively recruited confirmed T1D patients constituted the subjects for this case-control study. Subjects included 52 males (52%) and 48 females (48%). The age range and mean range was 25-60 years and 42.45 years ± 12.23 years respectively. Forty age and gender-matched non-diabetics were monitored as controls. The packed cell volume, platelet and total white cell count and blood glucose level was determined using standard methods and results were compared statistically with values obtained from non-diabetic controls. Results: The mean PCV was significantly lower among subjects with (T1D) (36.93 ± 2.19) compared to the non-diabetic controls (39.80 ± 2.24), p=0.003. Diabetics with poor glycaemic control had lower packed cell volume compared to those with lower blood sugar level. The mean platelet and total white cell count was significantly higher among diabetics compared to non-diabetic controls (464.76 ± 158.66 and 8.48 ± 3.27) compared to (297.13 ± 94.25 and 6.48 ± 2.12) p=0.0001 and 0.001 respectively..read more
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