|Metformin is the most commonly used drug for the treatment of type 2 diabetes. Insulin resistance, obesity and type 2 diabetes are all related to an increased risk of cancer, resulting in higher mortality. AMPK may act as a potential therapeutic target in the prevention and treatment of type 2 diabetes and insulin resistance. APC is a safe topical agent for healing chronic lower leg ulcers in patients with diabetes. Salicylates are able to improve insulin sensitivity in obese mice and in humans affected by type 2 diabetes and they have also been shown to reduce the risk of several cancers including colon, breast, and prostate cancers.
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