|Maternal conditions as hyperglycemia, anemia, glucocorticoides exposure and low-protein diet throughout pregnancy cause hypertension in the adult offspring rat that may be due, in part, to a deficit in neuron numbers. maternal hypertension during pregnancy results in reduced birth weight and a decreased area and number of glomeruli. structural changes in the pups of hypertensive mothers may lead to hypertension in adulthood these individuals. certain animal models of genetic hypertension and forms of human hypertension are associated with a decrease in NO synthesis.
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