Autonomic Nervous System (ANS) dysfunction (AuD) is a common cause of disability in people living with Multiple Sclerosis (MS), but clinical manifestations are heterogeneous and therapeutic options are lacking. AuD is implicated as having a possible role in the regulation of inflammation and neurodegeneration. treatments with drugs that affect the ANS may have an impact in the inflammatory and neurodegenerative processes intrinsic to MS, resulting in an intriguing and potentially significant novel therapeutic consideration. AuD is a common cause of disability in MS patients, ranging from sphincter (bladder and bowel) dysfunction, to fatigue and cardiovascular autonomic dysfunction (CAD), among others. Both the sympathetic (SNS) and parasympathetic (PNS) nervous systems are frequently, albeit not always simultaneously, compromised.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Last date updated on February, 2021